EFFICACY OF PANCRAGEN PEPTIDE IN ELDERLY PATIENTS WITH TYPE 2 DIABETES MELLITUS

Authors

  • Korkushko O. V. SI "Institute of Gerontology. DF Chebotaryov Academy of Medical Sciences of Ukraine ", Kyiv;
  • Shatilo V. B. SI "Institute of Gerontology. DF Chebotaryov Academy of Medical Sciences of Ukraine ", Kyiv;
  • Havinson W. H. Institute of Bioregulation and Gerontology of the Russian Academy of Medical Sciences, St. Petersburg
  • Antonyuk-Shcheglova I. A. Institute of Bioregulation and Gerontology of the Russian Academy of Medical Sciences, St. Petersburg

DOI:

https://doi.org/10.21856/j-PEP.2010.3.01

Keywords:

type 2 diabetes mellitus, elderly patients, glibenclamide, tetrapeptide pankragen, efficacy

Abstract

The paper shows that in elderly patients with uncompensated diabetes 2 types of course application of the drug Pankragen (RF Patent № 2242241) on Against the background of constant doses of glibenclamide leads to a significant decrease in plasma glucose levels on an empty stomach and 2 hours after the oral glucose tolerance test. An additional sugar -free effect is preserved two weeks after the cancellation of the pankration in 60 % of patients who continued to take
glibenclamide in previous doses. Pankochen has an additional sugar -free effect in patients with high initial resistance to insulin
And hyperinSulinemia. Under the influence of the peptide preparation, the index decreases Homa insulin resistance. Any side effects or undesirable changes in laboratory indicators associated with the reception
Observing. Pankochen is shown to an elderly patient with an uncompensated course of type 2 diabetes with insufficient effectiveness of therapeutic
Glibenclamide dosages.

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Published

2010-10-12

How to Cite

Korkushko, O. V., Shatilo, V. B., Havinson, W. H., & Antonyuk-Shcheglova, I. A. (2010). EFFICACY OF PANCRAGEN PEPTIDE IN ELDERLY PATIENTS WITH TYPE 2 DIABETES MELLITUS. Problems of Endocrine Pathology, 33(3), 5-10. https://doi.org/10.21856/j-PEP.2010.3.01

Issue

Section

CLINICAL ENDOCRINOLOGY