BENEFITS OF CONTINUOUS GLYCEMIC MONITORING IN TYPE 1 DIABETES MELLITUS IN CHILDREN AND ADOLESCENTS

Authors

DOI:

https://doi.org/10.21856/j-PEP.2022.1.02

Keywords:

цукровий діабет 1 типу , діти, помпова інсулінотерапія, багаторазові ін’єкції інсуліну, безперервний моніторинг глікемії, глікозильований гемоглобін

Abstract

A comparative analysis of glycemic control in children and adolescents with type 1 diabetes mellitus (T1DM) on insulin therapy by the method of multiple insulin injections (MII) and pump insulin therapy (PIT), taking into account continuous glycemic monitoring (CGM). 193 children with T1DM were divided into 3 groups: group I - PIT with CMG (n = 32) group II - MII with CMG (n = 75); group III - MII with self-monitoring of glucose 4-8 times a day, without CMG (n = 86). In the first group the level of HbA1c was 6,9 ± 0,19% (P (I - III) < 0,001), in the second group - 7,1 ± 0,14% (P II-III< 0,001) and in the III group - 8,7 ± 0,43%. In the I and II groups the level of HbA1c was near to the target glycemia indicator. Conclusions: Glycemic control of T1DM depends on the use of a set of methods for monitoring glycemia with an assessment of glycemia variability and does not depend on the method of insulin therapy. It is advisable to conduct continuous monitoring of glycemia in children and adolescents with TDM1, regardless of the duration of the disease and the method of insulin therapy.

References

Patterson CC, Karuranga S, Salpea P, et al. Diabetes Res Clin Pract 2019;157: 107842. https://doi.org/10.1016/j.diabres.2019.107842.

ISPAD Clinical Practice Consensus Guidelines 2018. available at: https://www.ispad.org/page/ISPADGuidelines2018.

Danne T, Nimri R, Battelino T, et al. Diabetes Care 2017;40(12): 1631-1640.

Muz N, Samson O, Vyshnevska O, et al. J Endocrine Soc 2019;3(1). https://doi.org/10.1210/js.2019-SUN-140.

Johnson SR, Cooper MN, Jones TW, et al. Diabetologia 2013;56: 2392-2400.

Beck RW, Buckingham B, Miller K, et al. Diabetes Care 2009;32(11): 1947-1953.

Ly TT, Nicholas JA, Retterath A, et al. JAMA 2013;310: 1240-1247.

Weinzimer S, Xing D, Tansey M, et al. Pediatr Diabetes 2009;10(2): 91-96.

Perkins BA, Halpern EM, Orszag A, et al. Can J Diabetes 2015;39(1): 50-54.

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Published

2022-03-15

How to Cite

Большова, О., Самсон, О., Лукашук, І., Спринчук, Н., Маліновська, Т., Музь, Н., Пахомова, В., Вишневська, О., & Кваченюк, Д. (2022). BENEFITS OF CONTINUOUS GLYCEMIC MONITORING IN TYPE 1 DIABETES MELLITUS IN CHILDREN AND ADOLESCENTS. Problems of Endocrine Pathology, 79(1), 15-19. https://doi.org/10.21856/j-PEP.2022.1.02

Issue

Section

CLINICAL ENDOCRINOLOGY