STATUS OF INTRARENAL HEMODYNAMICS AND TUBULAR KIDNEY APPARATUS IN NORMOALBUMINURIC CHILDREN WITH 1 TYPE DIABETES MELLITUS

Authors

  • Makeyeva N. I. Kharkiv National Medical University

DOI:

https://doi.org/10.21856/j-PEP.2010.1.08

Keywords:

intrarenal hemodynamics, urine excretion of β2-microglobulin, 1 type diabetes mellitus, children

Abstract

It was shown the decreased or absent renal functional reserve in diabetic normoalbuminuric patients with a normal level of glomerular rate filtration indicates the diabetic damage of kidney vessel apparatus. The increased β2-microglobulin excretion in children with 1 type diabetes mellitus is specified as a tubular dysfunction marker and ground for early diagnostics of diabetic nephropathy.

References

Nephropathy in Diabetes (American Diabetes Association) [Text] // Diabetes Care. — 2004. — Suppl. 1. — P. 79–83.

Levy G. Handbook of Dialysis [Text] / G. Levy, G. Morgan. — Oxford: Oxford University Press, 2002. — 400 p.

Patients with diabetic nephropathy on renal replacement therapy in England and Wales [Text] / D. Nitsch, R. Burden, R. Steenkamp [et al.] // QJM. — 2007. — Vol. 100 (9). — P. 551–560.

Касаткина Э. П. Сахарный диабет у детей и подростков [Текст] / Э. П. Касаткина. — М.: Медицина, 1998. — 240 с.

Дедов И. И. Диабетическая нефропатия [Текст] / И. И. Дедов, М. В. Шестакова. — М.: Универсум Паблишинг, 2000. — 240 с.

Paul E. de Jong. Screening for early chronic kidney disease — what method fits best? [Text] / Paul E. de Jong, Nynke Halbesma, Ron T. Gansevoort // Nephrol. Dialys. Transplant. — 2006. — Vol. 21 (9). — P. 2358–2361.

Renal functional reserve in humans [Text] / J. P. Bosch, A. Saccaggi, A. Lauer [et al.] // Am. J. Med. — 1983. — Vol. 75. — P. 943–950.

Brenner B. M. Hemodynamically mediated glomerular injury and progressive nature of kidney disease [Text] / B. M. Brenner // Kidney Inst. — 1983. — Vol. 23. — P. 647–655.

Glomerular hyperfiltration predicts the development of microalbuminuria in stage 1 hypertension: the HAR-VEST [Text] / P. Palatini, P. Mormino, F. Dorigatti [et al.] // Kidney Int. — 2006. — Vol. 70, № 3. — P. 578–584.

Смирнов А. В. Хроническая болезнь почек: на пути к единству представлений [Текст] / А. В. Смирнов, А. М. Есаян, И. Г. Каюков // Нефрология. — 2002. — № 4. — С. 11–17.

Spectrum of renal diseases associated with extreme forms of insulin resistance [Text] / C. Musso, E. Javor, E. Cochran [et al.] // Clin. J. Am. Soc. Nephrol. — 2006. — Vol. 1, № 4. — P. 616–622.

Diabetes-induced hyperfiltration in adenosine A(1)-receptor deficient mice lacking the tubuloglomerular feedback mechanism [Text] / J. Sällström, P. O. Carlsson, B. B. Fredholm [et al.] // Acta Physiol. — 2007. — Vol. 5. — P. 135–139.

Fede C. N-acetyl-beta-D-glucosaminidase and beta2-microglobulin: prognostic markers in idiopathic nephrotic syndrome [Text] / C. Fede, G. Conti, R. Cimenz, M. Ricca // J. Nephrol. — 1999. — № 12 (1). — P. 51–55.

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Published

2010-03-03

How to Cite

Makeyeva, N. I. (2010). STATUS OF INTRARENAL HEMODYNAMICS AND TUBULAR KIDNEY APPARATUS IN NORMOALBUMINURIC CHILDREN WITH 1 TYPE DIABETES MELLITUS . Problems of Endocrine Pathology, 31(1), 55-59. https://doi.org/10.21856/j-PEP.2010.1.08

Issue

Section

CLINICAL ENDOCRINOLOGY