ASSESSMENT OF THE PLATELET COMPONENT OF HEMOSTASIS IN RATS WITH METABOLIC SYNDROME AGAINST ESTROGEN DEFICIENCY

Authors

  • Gorbenko N. I. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv https://orcid.org/0000-0001-6598-730X
  • Oksenenko S. V. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv
  • Ivanova O. V. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv https://orcid.org/0000-0002-2807-8729
  • Borikov O. Yu. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv https://orcid.org/0000-0001-5776-566X
  • Stepanova A. V. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv
  • Taran K. V. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv
  • Zvyagina T. S. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv

DOI:

https://doi.org/10.21856/j-PEP.2010.3.10

Keywords:

Обрані:experimental metabolic syndrome, deficiency estrogens, platelet aggregation

Abstract

The platelet component of hemostasis in rats with metabolic syndrome induced by a high-fat diet under conditions of eu- and hypoestrogenism. It was found that in females receiving a high-fat diet, there is an increase in the degree, and in ovariectomized rats kept on a standard diet, the rate of ADP-induced platelet aggregation increases. The combined effect of diet and estrogen deficiency causes a more pronounced increase of both studied indicators, which indicates the summation of their procoagulant effect.

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Published

2010-10-12

How to Cite

Gorbenko, N., Oksenenko, S. V., Ivanova, O., Borikov, O., Stepanova, A. V., Taran, K. V., & Zvyagina, T. S. (2010). ASSESSMENT OF THE PLATELET COMPONENT OF HEMOSTASIS IN RATS WITH METABOLIC SYNDROME AGAINST ESTROGEN DEFICIENCY. Problems of Endocrine Pathology, 33(3), 66-68. https://doi.org/10.21856/j-PEP.2010.3.10

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