CHANGES IN THE SYSTEM PLACENTA - FETUS WITH SMOKING PREGNANTS AS BACKGROUND OF THYROPATHIES IN OFFSPRING

Authors

  • Sergiyenko L. Yu. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv
  • Yakovtsova I. I. 2Kharkiv Postgraduate Medical Academy
  • Sokolova S. S. 1SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv; Kharkiv Postgraduate Medical Academy
  • Selyukova N. Yu. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv

DOI:

https://doi.org/10.21856/j-PEP.2015.3.15

Keywords:

system of «placenta – fetus» , smoking pregnant, offspring, thyropathies.

Abstract

It was found that the intake of nicotine by rats of pregnant females in conjunction with a reduction in the volume of food consumed has a significant impact on the system of «placenta – fetus» in offspring of both sexes, significantly reducing the morphological and functional characteristics and capabilities of the placenta due to toxic and vasoconstrictor effects of nicotine. Toxic effects of nicotine, even in low doses, in pregnant females during passive smoking leads to fetal and postnatal death of a high percentage of fetuses and is a predictor of deep changes in the structure and hormone-producing function of the offspring thyroid glands.

References

Janjuta SM, Dashkevych VS, Tarahovs’kyj ML. Pediatrija, Akusherstvo i Ginekologija 1997; 5:65-68.

Kajantie E. An. NY Acad Sci 2006; 60:5-20.

Ward IL. Psychoneuroendocrinology 1984; 9:3-11.

Reznikov AG, Pishak VP, Nosenko ND, et al. Perinatal’nyj stress i nejrojendokrinnaja patologija, Chernovcy, 2004: 318 p.

Brunton PJ. Soc Reprod Fertil 2013; 146:175-189.

Sergijenko LJu. Social’no-emocijnyj stres materiv na rannih etapah vagitnosti jak prychyna endokrynopatij ta porushen’ u gormonal’no zalezhnyh systemah nashhadkiv, Harkiv, 2013: 42 p.

Saenger P, Czernichow P, Hughes I, Reiter EO. Endocr Rev 2007; 28:219-251.

Sastry BV, Chance MB, Hemontolor ME, GoddijnWessel TA. Pharmacology 1998; 57:104-116.

Suter M. Epigenetics 2011; 6:1284-1294.

Lips KS. Placenta 2005; 26:735-746.

Andersen KV, Hermann N. Acta Obstet Gynecol Scand 1984; 63:707-709.

Lindblad A, Marsal K, Andersson KE. Obstet Gynecol 1988; 72:371-382.

Castro LC. Obstet Gynecol 1993; 81:551-555.

Salafia C, Shiverick K. Placenta 1999; 20:273-279.

Lambers DS, Clark KE. Semin Perinatol 1996; 20:115-126.

Mantzoros CS. J Clin Endocrinol Metab 1997; 82:2856- 2861.

Coutant R. J Clin Endocrinol Metab 2001; 86:4854-4859.

Shields B. J Clin Endocrinol Metab 2009; 94:570-574.

Bagnoli F, Laura F, Sara N, Salvatore G. J Clin Res Pediatr Endocrinol 2013; 5(1):2-7.

Wojtyła A, Gozdziewska M, Paprzycki P, Bilinski P. Ann Agricult Environmen Med 2012; 19(1):117-128.

Sokolova SS. Probl Endokryn Patologii’ 2015; 1:113-119.

Sergijenko LJu. Probl Endokryn Patologii’ 2015; 2:110-118.

Wickstrom R. Curr Neuropharmacol 2007; 5:213-222.

Downloads

Published

2021-08-17

How to Cite

Sergiyenko, L. Y. ., Yakovtsova, . I. I. ., Sokolova, S. S., & Selyukova, N. Y. . (2021). CHANGES IN THE SYSTEM PLACENTA - FETUS WITH SMOKING PREGNANTS AS BACKGROUND OF THYROPATHIES IN OFFSPRING. Problems of Endocrine Pathology, 53(3), 118-125. https://doi.org/10.21856/j-PEP.2015.3.15

Issue

Vol. 53 No. 3 (2015): Problems of Endocrine Pathology

Section

EXPERIMENTAL STUDIES

Most read articles by the same author(s)

1 2 > >>