• Biliaieva K. S. National Pirogov Memorial Medical University, Vinnytsya, Ukraine;
  • Vlasenko M. V. National Pirogov Memorial Medical University, Vinnytsya, Ukraine;
  • Pashkovska N. V. Bukovinian State Medical University, Chernivtsi, Ukraine



vitamin D, type 1 diabetes, adolescents, carbohydrate metabolism


Based on current world data, vitamin D deficiency as well as insufficiency is one of the health problems
worldwide and has a global pandemic meaning for the population. Vitamin D is involved in many physiological processes that occur in the body, which are especially important during puberty, period of intensive growth
and a set of peak bone mass of the child. According to the latest data of vitamin D effects on the development
and prognosis of type 1 diabetes mellitus, the aim of the study was to determine the epidemiology of vitamin D
deficiency and insufficiency in adolescents with type 1 diabetes mellitus, as well as to assess the correlation
between levels of vitamin D and compensation of the disease. The study was conducted on the basis of the
Vinnitsya regional clinical highly specialized endocrinological center. The total number of examined patients
was 124 adolescents aged from 10 to 18 years (61 girls, 63 boys), including: 1 group — 91 adolescents with type 1
diabetes, 2 group — 33 healthy adolescents (16 girls, 17 boys). According to the results of the study, the majority
of adolescents with type 1 diabetes have a deficiency (69 %) or insufficiency (26 %) of vitamin D. Only 5 % of the
examined adolescents had normal levels of vitamin D. In the group of somatically healthy adolescents, normal
levels of vitamin D were observed in 15% of children. It has been established that the prevalence of vitamin D
deficiency in adolescents with type 1 diabetes mellitus is higher compared to healthy adolescents. Also it was
found that the bigger part of the patients with type 1 diabetes mellitus who has poor glycemic control had vitamin D deficiency. Further studies should be held for evaluation of glycemic control in adolescents with type 1
diabetes mellitus after normalization of vitamin D levels


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How to Cite

Biliaieva, K. S., Vlasenko, M. V., & Pashkovska, N. V. (2020). VITAMIN D STATUS IN ADOLSECENTS WITH TYPE 1 DIABETES MELLITUS. Problems of Endocrine Pathology, 72(2), 16-24.